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Chitooligosaccharide and chitosan as the basic conditions of functional health food

BZ Oligo

1. Regulate the pH of the body

The molecular structure of chitosan oligosaccharide and chitosan has an amino group (-NH2) with a positive charge and is alkaline. The pH of normal metabolism in the human body is pH 7.35 to 7.45, which is the optimal metabolic environment. In chronic diseases and sub-health states, the pH value of the body decreases and tends to be acidic. After taking chitosan oligosaccharide and chitosan, the pH value of blood and tissue fluid is increased to improve the acidic environment, which is beneficial to the prevention and recovery of diseases.

2. Improve immunity, assist anti-cancer and anti-tumor

Lei Chaoliang et al. injected 5ml, 10ml and 20ml of 2% chitosan aqueous solution into the abdominal cavity of mice, and found that chitosan could increase the activity of peritoneal macrophages and NK cells in mice, and enhanced both cellular and humoral immunity. effect. In addition, the hexameric product (COS-6) produced by the degradation of chitosan has strong antitumor activity. Ma Xiaozhen reported that the mechanism of chitosan's ability to enhance immunity and anti-tumor function may be: chitosan is a positive chemotactic agent, adsorbs monocytes to swim out of blood vessels, aggregates in tissues, and forms macrophages (immune cells); shell Glycan can adsorb H+, so it has a large amount of NH3+, which enhances its affinity, activates macrophages, increases its affinity by 3 times, and increases the activity of NK cells by 4.5 times, increasing intracellular biological activity. It can also activate T cells (immune cells) to release various lymphokines; the positive charge on the surface of chitosan has affinity with the negative charge on the surface of the tumor, Directly inhibit the activity of cancer cells.

3. Antioxidant, scavenging free radicals

Free radicals, also known as active oxygen, strong oxygen (including O2, OH-, H. O2, iso-oxygen radicals, hydroxyl radicals) are extremely small particles, a group of groups with high chemical reactivity, which can be called hundred The culprit of disease, the source of all evil. There are two sources: one is produced by the human body’s own metabolism. Usually most of the oxygen molecules are inhaled for the body to use and safely excreted, but a small part of the oxygen molecules are converted into free radicals in the process of oxidative metabolism; the other is due to environmental pollution, Ionizing radiation, photochemical pollution and other external factors, plus smoking, alcoholism, eating junk food such as barbecue and frying. Free radicals can accelerate aging, reduce human immunity, and cause various diseases such as cancer, leukemia, hypertension, myocardial infarction, diabetes, hepatitis, gout, nephritis, and cataract.

Because of its small molecular weight, good solubility, strong osmotic power and affinity, chitosan oligosaccharide easily penetrates the human cell membrane, improves microcirculation, and exerts its health effects of disease prevention and adjuvant therapy. It can be said that chitosan oligosaccharide is the guardian of the body from free radical damage. Domestic researches such as He Qingde, Xu Guiyun, Wu Hongjun, etc. have proved that chitosan oligosaccharide can scavenge free radicals, improve the activity of antioxidant enzymes (superoxide dismutase, SOD), inhibit the activity of free radicals and improve the effect of anti-fatigue.

BZ Oligo mainly offer marine oligosaccharide standards and ingredients, containing alginate oligosaccharide, chitosan oligosaccharide, agar oligosaccharide and carrageenan oligosaccharide, which give business opportunities using these untapped oligosaccharides for biological applications targeting lab research, pharmacy, dietary supplement, sustainable agriculture and animal health. 

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